Personalized, Predictive, Preventive, and Participatory medicine for Respiratory diseases

Last decade we are witnessing change from traditional reactive approach to new complex P4 assessment of diseases. The P4 medicine is a proposed new form of medical practice that combines Personalized, Predictive, Preventive, and Participatory elements. This new paradigm with success can be applied for management of respiratory diseases. For example: what does P4 medicine mean for COPD? It will be “personalized” because it will be based on the genome of each person; it will be “predictive” because this personalized information will be able to determine the risk for COPD in each individual; it will be “preventive” because, given the prediction of risk of COPD, prophylactic measures will be able to be taken to decrease risk also with accent on awareness in each individual case; and it will be “participative” because many of these prophylactic interventions will require the participation of the COPD patient.

Defining COPD: from simplistic approach to multilateral assessment of COPD

My article Defining COPD: from simplistic approach to multilateral assessment of COPD is appearing online today in Spinger Journal -  Current Respiratory Care Reports. Current Respiratory Care Reports provides clear expert reviews of the most important original papers recently published in the field of respiratory care.  

A source for current research, diagnostic and management techniques for patients with respiratory-related disorders

• Offers expert reviews of important recent research papers in the field of respiratory care
• Provides supplementary reviews, featuring recent clinical trials
• Presents commentaries from well-known figures in the field.

Defining COPD: from simplistic approach to multilateral assessment of COPD

Abstract  of my article:

Chronic obstructive pulmonary disease (COPD) is a multisystemic pathology, which cannot be characterized, diagnosed or assessed only by the severity of airflow limitation. Thus, it appears there is urgent unmet need of new approach in COPD. In this article we review the most recent multidimensional classification of COPD, based on analysis of functional and physiologic parameters, health status, and risk of exacerbations. A, B, C, D system will permit a more accurate risk stratification of patients. In addition, new trends are presented in assessment of COPD: from phenotypes, multidimensional indices, scale-free networks and diseasome to radical concept of P4 medicine (Personalized, Predictive, Preventive, and Participatory elements).  

Keywords   

COPD – Comorbidity – Exacerbation – CAT – Systemic effects – Assessment – GOLD classification – Severity – Phenotypes – Scale-free networks – Diseasome

Respiratory Masterclass in COPD and Asthma, Dubai, 21-22 January 2012

Dear Respiratory friends,

I want to share with you my experience from Respiratory Masterclass in COPD and Asthma which took place in Dubai, 21-22 January 2012. The meeting was dedicated to the new COPD and Asthma guidelines, which were launched recently.

There were 2 days full of new knowledge and experience. Faculty team was conducted by Professor Paul Jones from St Georges University of London, UK - world-known leader in respiratory research. Everybody knows his questionnaire: Saint-George Respiratory Questionnaire (SGRQ) which became classical, was validated in many languages and new one COPD Assessment Test (CAT test), which became the part of new GOLD classification of COPD.

There were many brilliant presentations by world opinion leaders in Asthma and COPD. Professor David Manino from University of Kentucky College of Public Health Lexington, USA presented new statistical data about COPD: COPD: the big picture.

Professor Wisia Wedzicha from London, UK presented results of ECLIPSE Study.

Professor Neil Barnes from London, UK dedicated his presentation to the new treatment implications of the 2011 GOLD guideline.