Dear Respiratory Friends today is World Diabet Day 2014!
Diabetes may act as an independent factor negatively affecting
lung structure and function. Diabetes can cause muscle and neuronal damage, which
is relevant to deficient function of respiratory muscles. Moreover, diabetes is independently
associated with lower physical performance, which can be disabling for patients with
COPD, who already have some limitation in physical performance.
DM is able to detrimentally
affect alveolar capillary membrane and decrease DLCO, similarly to other microangiopathic
complications, such as diabetic nephropathy. Furthermore, DM is associated with the
presence of glucose in airway secretions, and this may contribute to the increased
risk of pulmonary infections seen in diabetics. MetS can increase the risk of COPD
exacerbation, and diabetes is associated with worsened outcomes of COPD flares. On
the top of that, coexistent OSA may increase the risk for type 2 DM in some individuals.
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