HOT TOPIC ISSUE OF CURRENT RESPIRATORY MEDICINE REVIEWS: SLEEP APNEA AND COMORBIDITIES

Dear Respiratory friends today online is appearing

Current Respiratory Medicine Reviews, Volume 11 - Number 4 - See more at: http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/11/issue/4/#sthash.EB2jbZQb.dpuf

our proposed hot-topic issue of Current Respiratory Medicine Reviews, Volume 11, Number 4: is an update on the assessment of the main comorbidities and management of patients with OSAS and comorbidities (hypertension, obesity, diabetes, stroke, heart failure, COPD, chronic kidney disease).
Guest Editor: Alexandru Corlateanu
Editor-in-Chief: Joseph Varon
9 articles + Editorial from Guest Editor! 

1. Alexandru Corlateanu. Editorial from Guest Editor: Current Management of Sleep Apnea and Comorbidities

 

Editorial from Guest Editor: Current Management of Sleep Apnea and Comorbidities - See more at: http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/11/issue/4/#sthash.EB2jbZQb.dpuf

Editorial from Guest Editor: Current Management of Sleep Apnea and Comorbidities - See more at: http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/11/issue/4/#sthash.EB2jbZQb.dpuf

Editorial from Guest Editor: Current Management of Sleep Apnea and Comorbidities - See more at: http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/11/issue/4/#sthash.EB2jbZQb.dpufOana Claudia Deleanu, Ana-Maria Nebunoiu, Miruna Mihaela Micheu, Andra Elena Malaut and Florin Dumitru Mihaltan.2. Oana Claudia Deleanu, Ana-Maria Nebunoiu, Miruna Mihaela Micheu, Andra Elena Malaut and Florin Dumitru Mihaltan.

2. Oana Claudia Deleanu, Ana-Maria Nebunoiu, Miruna Mihaela Micheu, Andra Elena Malaut and Florin Dumitru Mihaltan.

Relation between Obstructive Sleep apnea Syndrome and Resistant Hypertension - the Tip of the Iceberg
3. Victoria Chatzimavridou Grigoriadou, Alexander Mathioudakis, Alexandru Corlateanu, George Mathioudakis, Efstathia Evangelopoulou.
Obstructive Sleep Apnea and Hypertension: A Bidirectional Causal Relation
4. Stefan Mihaicuta, Izabela Anita Toth, Sorin Paralescu, Carmen Ardelean, Stefan Marian Frent and Oana Claudia Deleanu
Obesity and Body fat Distribution as Predictors for Obstructive Sleep Apnea Syndrome
5. Marius Balint Gib, Christophe Aron, Svetlana Ilie, Frederic Wallyn, Macha Tetart, Dumitrita Balint Gib.
The links between Sleep Apnea and Chronic Kidney Disease
6. Mastrodima-Polychroniou Sofia, Panoulis Konstantinos.
Pregnancy and Sleep Apnea
7. Alexandru Corlateanu, Victor Botnaru, Victoria Sircu, Serghei Covantev, Gloria Montanari.
Obstructive Sleep Apnea and Type 2 Diabetes: Dual Interaction
8. Andriana Papaioannou, Konstantinos Kostikas, Spyros Papiris.
Sleep Apnea and Coronary Heart Disease: from Dusk Till Dawn and Further
9. Silvia V. Dumitru, Epameinondas N Kosmas.
Stroke as a Consequence of Sleep Apnea: Epidemiology, Pathophysiology and Treatment Strategies
10. Alexandru Corlateanu, Victor Botnaru, Alexander G. Mathioudakis, Victoria Sircu, Nikos Siafakas.
Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnoea: A two-faced Janus
http://benthamscience.com/journals/current-respiratory-medicine-reviews/volume/11/issue/4/

Predictors of daytime sleepiness in patients with obstructive sleep apnea (fulltext from Pneumologia)

Background. The main symptomatic criterion to diagnose obstructive sleep apnea (OSA) is the level of daytime sleepiness. The Epworth Sleepiness Scale is a simple, self-administered questionnaire which provides a measurement of the subject’s general level of daytime sleepiness.
The aim of this study was to investigate the factors that can predict daytime sleepiness in patients with sleep apnea.

Methods. 50 consecutive patients with obstructive
sleep apnea were enrolled into the study. Age, gender, anthropometric and polygraphic data were
thoroughly analyzed. In all subjects daily sleepiness was assessed by Epworth Sleepiness Scale.
Results. The mean age of the subjects was 54.7±12.8 years, 82% males. The mean BMI was 31.9±6 kg/m2. Pearson correlation coefficient analysis demonstrates a significant positive correlation between the Epworth Sleepiness Scale and the desaturation index (r=0.31, p<0.01) and arterial hypertension (r=0.32, p<0.01). The forward stepwise regression analysis shows that the apnea hypopnea index and desaturation index are important predictors of daytime sleepiness in patients with obstructive sleep apnea which explains 40% of the Epworth Sleepiness Scale score.
Conclusion. The desaturation index showed the
strongest correlation with the Epworth scale. According to the results of the backward stepwise multiple regression and logistic regression, the predictors for the level of daytime sleepiness are oAHI and index of desaturation. According to the analysis of the ROC curve, desaturation index is a predictor of a high specificity.

fulltext:

https://www.researchgate.net/publication/283490885_Predictors_of_daytime_sleepiness_in_patients_with_obstructive_sleep_apnea

2015 Official ATS/ERS Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation

Rationale: Pulmonary rehabilitation (PR) has demonstrated physiological, symptom-reducing, psychosocial, and health economic benefits for patients with chronic respiratory diseases, yet it is underutilized worldwide. Insufficient funding, resources, and reimbursement; lack of healthcare professional, payer, and patient awareness and knowledge; and additional patient-related barriers all contribute to the gap between the knowledge of the science and benefits of PR and the actual delivery of PR services to suitable patients.

Objectives: The objectives of this document are to enhance implementation, use, and delivery of pulmonary rehabilitation to suitable individuals worldwide.
Methods: Members of the American Thoracic Society (ATS) Pulmonary Rehabilitation Assembly and the European Respiratory Society (ERS) Rehabilitation and Chronic Care Group established a Task Force and writing committee to develop a policy statement on PR. The document was modified based on feedback from expert peer reviewers. After cycles of review and revisions, the statement was reviewed and formally approved by the Board of Directors of the ATS and the Science Council and Executive Committee of the ERS.

Main Results: This document articulates policy recommendations for advancing healthcare professional, payer, and patient awareness and knowledge of PR, increasing patient access to PR, and ensuring quality of PR programs. It also recommends areas of future research to establish evidence to support the development of an updated funding and reimbursement policy regarding PR.

Conclusions: The ATS and ERS commit to undertake actions that will improve access to and delivery of PR services for suitable patients. They call on their members and other health professional societies, payers, patients, and patient advocacy groups to join in this commitment.

Read More: http://www.atsjournals.org/doi/abs/10.1164/rccm.201510-1966ST#.Vmvjnr_eqUk

New Inspirational Book: Waiting Time: My life before and after the lung transplantation

Dear Respiratory Friends today we are very happy to present you great Inspirational book by Barbara Eyrich from Germany - Waiting Time: My life before and after the lung transplantation!!
Several words about book from author Barbara Eyrich: 
This book is neither meant to be a medical treatise on my histology - COPD / PULMONARY EMPHYSEMA - nor a guide or decision-making aid for or against a lung transplant. It is also not supposed to be a pure boring biography. Plus - it is furthermore not my intention to settle up with anybody or cope with certain incidences, even if the one or other reader might get this impression. The book simply describes this time of my life: How the illness started, the waiting period prior to my transplantation with all the preparations, and the wait for a donor organ, the transplantation itself - and what happened afterwards. 

How did I feel and do during this long WAITING TIME? There were quite a few relapses I had to suffer from and to handle. How did I manage to overcome them? What had helped me, and who was involved? How did it happen that I had to decide on a transplantation? , and finally, how did I continue after the surgery?
For some readers it will not be easy to cope with those details, as I do come up with a lot of negative things. But: That's the way it was and is - and therefore I have to describe how they happened and how my overall condition is right now. Life, despite all positive thoughts and desires, often turns out completely differently than expected in the long- run. Such experiences cannot be found in any brochure, as life writes an individual story for each human being.
All the names of people mentioned in this book have been changed, abbreviated or made up in order to protect their identities. Similarities in name of living persons are purely coincidental or have been approved. Please wait...! Isn't this something we all have experienced at some point of time? Everyone reacts differently to these two words. One bangs on the table, is not willing to wait and wants everything to be instantly done. For the next one standing at the bus stop time gets too long; he starts running off too early and eventually misses the bus which arrives shortly after he has gone away and which leaves without him. Someone else patiently endures the waiting time, though seething inside. Yet another one deals with the waiting time, prepares for the things to come and does not even realize how quickly or slowly time passes by, and suddenly - the wait is over. As for my book: I want to picture my story; how it all began with the chronic disease COPD and the pulmonary emphysema, and all the ups and downs. I will show you insight into my private and inner self, and will describe the people who have accompanied me on my way: Clinical personnel, doctors, physiotherapists, companions from my Lungensport group (special breathing techniques), support groups, church, family, friends, and neighbors, simply the entire social environment. During this time, there was a lot I had to endure and to cope with; till this very day I wonder how I was able to manage everything. 

LINK:

http://www.amazon.com/dp/B0189MIFHU/ref=cm_sw_r_fa_awdm_rL-twb1ZAHB11

World COPD Day 2015

World COPD Day is organized by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in collaboration with health care professionals and COPD patient groups throughout the world. Its aim is to raise awareness about chronic obstructive pulmonary disease (COPD) and improve COPD care throughout the world
Each year GOLD chooses a theme and coordinates preparation and distribution of World COPD Day materials and resources. World COPD Day activities are organized in each country by health care professionals, educators, and members of the public who want to help reduce the burden of COPD.
The first World COPD Day was held in 2002. Each year organizers in more than 50 countries worldwide have carried out activities, making the day one of the world's most important COPD awareness and education events.

World COPD Day 2015 is taking place on Wednesday, November 18 around the theme “It’s Not Too Late.” This positive message was chosen to emphasize the meaningful actions people can take to improve their respiratory health, at any stage before or after a COPD diagnosis.

World Diabetes Day 2015

World Diabetes Day, on the 14th November every year, has grown from humble beginnings to become a globally-celebrated event to increase awareness about diabetes.

Comprising hundreds of campaigns, activities, screenings, lecture, meetings and more, World Diabetes Day is proving internationally effective in spreading the message about diabetes and raising awareness for the condition.

 

The theme of World Diabetes Day, from 2014 to 2016 will be healthy living and diabetes and this year, there’s a focus on starting each day right by having a healthy breakfast.

A healthy breakfast should help blood sugar levels from getting too high and should keep you full through the morning. Whilst cereal and toast may be cheap, these options typically raise blood sugar levels rapidly and may leave you hungry again before lunch.

If you drink fruit juice for breakfast, consider cutting the juice out or having a smaller glass of it. For reference, a 150ml glass of unsweetened orange juice contains around 15g of carbohydrate and 13g of sugar.

Obstructive sleep disordered breathing in 2–18 year-old children: diagnosis and management

The ERS Task Force on the Diagnosis and Management of Obstructive Sleep-Disordered Breathing (SDB) in Childhood has published a new document detailing a stepwise management approach for SDB in children aged 2–18.

The seven-step management approach covers topics such as reported symptoms, morbidities, treatment indications and follow-up evaluations. The document also takes into account the available diagnostic facilities and accepted treatment policies in different European countries, describing diagnostic modalities that can be used as alternatives for settings where polysomnography is not available.

This document summarises the conclusions of a European Respiratory Society Task Force on the diagnosis and management of obstructive sleep disordered breathing (SDB) in childhood and refers to children aged 2–18 years. Prospective cohort studies describing the natural history of SDB or randomised, double-blind, placebo-controlled trials regarding its management are scarce. Selected evidence (362 articles) can be consolidated into seven management steps. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are present (step 1). Central nervous or cardiovascular system morbidity, growth failure or enuresis and predictors of SDB persistence in the long-term are recognised (steps 2 and 3), and SDB severity is determined objectively preferably using polysomnography (step 4). Children with an apnoea–hypopnoea index (AHI) >5 episodes·h⁻¹, those with an AHI of 1–5 episodes·h⁻¹ and the presence of morbidity or factors predicting SDB persistence, and children with complex conditions (e.g. Down syndrome and Prader–Willi syndrome) all appear to benefit from treatment (step 5). Treatment interventions are usually implemented in a stepwise fashion addressing all abnormalities that predispose to SDB (step 6) with re-evaluation after each intervention to detect residual disease and to determine the need for additional treatment (step 7).

Link:

http://erj.ersjournals.com/content/early/2015/11/05/13993003.00385-2015?utm_source=ERS+newsletter&utm_campaign=ed0dc225f7-ER_Weekly_week_45&utm_medium=email&utm_term=0_372fc3467c-ed0dc225f7-35104157