Updated recommendations on influenza vaccination for the 2015-16 season have been issued by the CDC's Advisory Committee on Immunization Practices. As reported in MMWR, changes from the 2014-2015 season include the following:
- Trivalent vaccines will include A/California/7/2009 (H1N1)-like virus, an A/Switzerland/9715293/2013 (H3N2)-like virus, and a B/Phuket/3073/2013-like (Yamagata lineage) virus. These A (H3N2) and B viruses are different from the previous season.
- The Fluzone Intradermal Quadrivalent vaccine is expected to replace the trivalent Fluzone Intradermal vaccine for adults aged 18 to 64.
- Children aged 6 months to 8 years who are receiving their first influenza vaccine still need two doses at least 4 weeks apart, but special consideration of influenza A(H1N1)pdm09 vaccination is no longer needed, since current vaccines incorporate that viral antigen.
- Live-attenuated vaccine (previously preferred for children aged 2–8 years) is no longer recommended over inactivated vaccine, because observational studies failed to support the superiority of live-attenuated vaccine seen in randomized trials.