Dear friends we are happy to present you new interesting review on new clinical entity: chronic respiratory symptoms in persons with normal spirometry!
The 2001 Global Initiative for Chronic Obstructive Lung
Disease (GOLD) Report defined five stages of spirometric severity
(post-bronchodilator FEV1/FVC≥0.7): 0, and 1 (mild) to 4 (very severe).
GOLD Stage 0 was defined by chronic cough and sputum production or
chronic mucus hypersecretion (CMH) alone with preserved FEV1/FVC.
Subsequently, GOLD 0 was discarded as further evidence of COPD
development in subjects with GOLD 0 was not more likely to develop.
When
expanding symptomatic burden in GOLD 0 to include other chronic
respiratory symptoms, such as dyspnea, wheeze, poor quality of life,
limited physical activity, and ‘COPD exacerbations-like’ events needing
health resources, symptomatic smokers with normal FEV1 resulted in
larger risk of death. We review the evidence supporting a relationship
between an increased symptom burden, long-term FEV1 decline and
development of COPD. We also address the evidence for the presence of
respiratory symptoms with normal FEV1 in smokers as a potential clinical
entity. This subset of symptomatic patients encompasses a compelling
category of smokers with normal spirometry but increased risk for poor
outcomes. What exactly these symptomatic patients with intact FEV1
represent remains unclear. Whether they exemplify smoking-induced just a
broadening of respiratory abnormalities or a distinct clinical entity
that precedes the development of COPD or both remains unknown. Other
aims, such as providing information on pathogenesis and future areas of
research, are just as vital. What ultimately prevails however is the
importance of the public health message to the frightening presence of
chronic respiratory symptoms in the whole population.
This design is wicked! You definitely know how to keep a reader amused. Between your wit and your videos, I was almost moved to start my own blog (well, almost...HaHa!) Fantastic job. I really loved what you had to say, and more than that, how you presented it. Too cool!
ReplyDeleteSkin Biopsy FL
I started on COPD Herbal treatment from Ultimate Life Clinic, the treatment worked incredibly for my lungs condition. I used the herbal treatment for almost 4 months, it reversed my COPD. My severe shortness of breath, dry cough, chest tightness gradually disappeared. Reach Ultimate Life Clinic via their website www.ultimatelifeclinic.com . I can breath much better and It feels comfortable!
ReplyDelete