Pulmonary rehabilitation and cardiovascular risk in COPD: a systematic review (Free Full text from 2017 COPD Research and Practice)
Pulmonary Rehabilitation (PR) is an effective
intervention in COPD however the value of PR in reducing cardiovascular risk in
COPD (measured by aortic pulse wave velocity, PWV) is unclear and there is no
existing systematic review.
Objectives To conduct a systematic review examining whether PR
results in alteration of CV risk in COPD (as measured by aPWV).
An electronic systematic search concordant with PRISMA
guidelines was conducted. The search was complete to the 27th of May 2017. Six
databases were examined: Embase, Medline, AMED, Web of Science, Cochrane
clinical trials, and CINAHL.
This study generated 767 initial matches, which were
filtered using inclusion/exclusion criteria. Three studies (201 COPD
participants) were included. Our analysis does not confirm that PR affects aPWV
but studies were heterogeneous.
There is currently insufficient information on the
effect of PR on reducing CV risk in COPD. Therefore controversy remains, with
the possibility that there might be some subjects who benefit and others who
might experience an increase in CV risk in response to PR. These results will
be of value to those interested in gaining a better understanding of the
benefits of PR on CV risk in COPD.