Roflumilast, a selective phosphodiesterase 4 inhibitor, has been shown
to provide modest improvements in lung function in patients with
mild-to-moderate asthma, but its efficacy in patients with
moderate-to-severe asthma has not been assessed. Authors hypothesized that
this drug might provide benefit if combined with montelukast, a
leukotriene receptor antagonist, in patients whose symptoms are
uncontrolled by inhaled corticosteroids and long-acting β-agonists.
The combination of roflumilast with montelukast compared with
montelukast alone improved lung function and asthma control in patients
with moderate-to-severe asthma and deserves further study for this
indication.
Free full text:
ReplyDeleteI’ve been living with Parkinson’s disease for some time, and nothing I tried seemed to make a lasting difference—until I began the herbal treatment from NaturePath Herbal Clinic. I was skeptical at first, but after about four months, I started to notice real improvements. My tremors became less frequent, my stiffness reduced, and my balance and coordination gradually began to improve.
For the first time in years, I feel more in control of my body and daily life. I can move more freely, sleep better, and even enjoy simple activities again without constant discomfort. The changes have been truly uplifting—both physically and emotionally.
If you're exploring natural options for managing Parkinson’s, I genuinely recommend giving this a try. It’s been a life-changing experience for me.
Learn more at their website.naturepathherbalclinic.com